Free PDF Development And Validation Of Analytical Methods Simultaneous Estimation Of Amlodipine Besilate And Indapamide In Bulk Drug And Tablet Dosage Form

[Ebook.cs6U] Development And Validation Of Analytical Methods Simultaneous Estimation Of Amlodipine Besilate And Indapamide In Bulk Drug And Tablet Dosage Form

[Ebook.cs6U] Development And Validation Of Analytical Methods Simultaneous Estimation Of Amlodipine Besilate And Indapamide In Bulk Drug And Tablet Dosage Form

You can download in the form of an ebook: pdf, kindle ebook, ms word here and more softfile type. [Ebook.cs6U] Development And Validation Of Analytical Methods Simultaneous Estimation Of Amlodipine Besilate And Indapamide In Bulk Drug And Tablet Dosage Form, this is a great books that I think are not only fun to read but also very educational.
Book Details :
Published on: 2012-10-05
Released on: 2012-10-05
Original language: English

Two UV-Spectrophotometric and RP-HPLC methods have been developed and validated for estimation of Amlodipine Besilate and Indapamide simultaneously.In absorbance correction method absorbance was measured at 360 nm for Amlodipine Besilate and at 242 nm for Indapamide. In First order Spectrophotometry method, the dA/dλ value in first order derivative spectra was measured at 242 nm for Amlodipine Besilate and 238 nm for Indapamide. The proposed methods were utilized for estimation of Amlodipine Besilate and Indapamide in tablet dosage form. RP-HPLC method showed adequate separation of Amlodipine Besilate and Indapamide. Amlodipine Besilate and Indapamide were estimated on C18 column using Acetonitrile: Water (contains 0.2% of Triethylamine and adjusting the pH to 4.0 with 10 % orthophosphoric acid) in a proportion of 70:30 v/v as mobile phase and detection was carried out at 238 nm. Results of Validation study and assay of all three methods were found to be satisfactory. The developed method were statistically compared using one way ANOVA which suggest that there is no significance difference among all three methods.
Free (Reprint) 1987 Yearbook Lewis Clark High School Spokane Washington